List of diseases covered by Left Ventricular Noncompaction Cardiomyopathy NGS panel

List of diseases covered by
Left Ventricular Noncompaction Cardiomyopathy
NGS panel

Gene Condition
ACTC1 Left ventricular noncompaction 4; Cardiomyopathy, hypertrophic, 11;
Atrial septal defect 5
CASQ2 Ventricular tachycardia, catecholaminergic polymorphic, 2
DTNA Left ventricular noncompaction 1, with or without congenital heart defects
LDB3 Left ventricular noncompaction 3; Myopathy, myofibrillar, 4
LMNA Muscular dystrophy, limb-girdle, type 1B;
Charcot-Marie-Tooth disease, type 2B1;
Cardiomyopathy, dilated, 1A;
Emery-Dreifuss muscular dystrophy 2, AD;
Emery-Dreifuss muscular dystrophy 3, AR;
Muscular dystrophy, congenital; Heart-hand syndrome, Slovenian type;
Lipodystrophy, familial partial, type 2; Malouf syndrome
MIB1 Left ventricular noncompaction 7
MYBPC3 Left ventricular noncompaction 10; Cardiomyopathy, hypertrophic, 4
MYH7 Left ventricular noncompaction 5; Cardiomyopathy, hypertrophic, 1;
Laing distal myopathy; Myopathy, myosin storage, autosomal dominant;
Myopathy, myosin storage, autosomal recessive;
Scapuloperoneal syndrome, myopathic type
PRDM16 Left ventricular noncompaction 8
TAZ Barth syndrome
TNNT2 Left ventricular noncompaction 6; Cardiomyopathy, familial restrictive, 3;
Cardiomyopathy, hypertrophic, 2
TPM1 Left ventricular noncompaction 9; Cardiomyopathy, hypertrophic, 3
VCL Cardiomyopathy, dilated, 1W; Cardiomyopathy, hypertrophic, 15

Left Ventricular Noncompaction Cardiomyopathy NGS panel

Left Ventricular Noncompaction Cardiomyopathy
NGS panel

Genes
(full
coding region):
ACTC1, CASQ2, DTNA, LDB3, LMNA, MIB1, MYBPC3, MYH7, PRDM16, TAZ, TNNT2, TPM1, VCL

List of diseases covered by the panel


Lab method: NGS panel
NGS panel with CNV

TAT: 6-9 weeks

Specimen requirements: 2-4 ml of blood with anticoagulant EDTA

1 µg DNA in TE, AE or pure sterile water at 100-250 ng/µl
The A260/A280 ratio should be 1.8-2.0. DNA sample should be run on an agarose gel as a single band, showing no degradation, alongside with a quantitative DNA marker.


Ordering information: Go to online ordering or download sample submission form