Hyper IgE syndrome

Genes (full coding region): CARD11, ERBIN (ERBB2IP), IL6R, IL6ST, PGM3, SPINK5, STAT3, TGFBR1, TGFBR2, ZNF341

Lab method: NGS panel with CNV analysis

TAT: 6-9 weeks

Specimen requirements: 2-4 ml of blood with anticoagulant EDTA


1 µg DNA in TE, AE or pure sterile water at 100-250 ng/µl
The A260/A280 ratio should be 1.8-2.0. DNA sample should be run on an agarose gel as a single band, showing no degradation, alongside with a quantitative DNA marker.

Ordering information: Go to online ordering or download sample submission form