List of diseases covered by
Noonan Syndrome NGS panel

Gene Condition
BRAF Noonan syndrome 7; LEOPARD syndrome 3;
Cardiofaciocutaneous syndrome
CBL Noonan syndrome-like disorder with or without juvenile
myelomonocytic leukemia
HRAS Costello syndrome
KAT6B Genitopatellar syndrome; SBBYSS syndrome
KRAS Noonan syndrome 3; Cardiofaciocutaneous syndrome 2
MAP2K1 Cardiofaciocutaneous syndrome 3
MAP2K2 Cardiofaciocutaneous syndrome 4
NRAS Noonan syndrome 6
PTPN11 Noonan syndrome 1; LEOPARD syndrome 1; Metachondromatosis
RAF1 Noonan syndrome 5; LEOPARD syndrome 2;
Cardiomyopathy, dilated, 1NN
SHOC2 Noonan-like syndrome with loose anagen hair
SOS1 Noonan syndrome 4
SPRED1 Legius syndrome