Familial Adenomatous Polyposis

Familial Adenomatous Polyposis
Sequencing of the APC gene

Genes: APC

Lab method: Sanger sequencing / Next generation sequencing

Price / TAT: 773 EUR / 2-4 weeks

Specimen requirements: 2-4 ml of blood with anticoagulant EDTA

2 µg DNA in TE, AE or pure sterile water at 100-250 ng/µl
The A260/A280 ratio should be 1.8-2.0. DNA sample should be run on an agarose gel as a single band, showing no degradation, alongside with a quantitative DNA marker.


Ordering information: Go to online ordering or download sample submission form

Del/dup analysis of the APC gene

Genes: APC

Lab method: MLPA

Price / TAT: 310 EUR / 4-6 weeks

Specimen requirements: 2-4 ml of blood with anticoagulant EDTA

1 µg DNA in TE, AE or pure sterile water at 100-250 ng/µl
The A260/A280 ratio should be 1.8-2.0. DNA sample should be run on an agarose gel as a single band, showing no degradation, alongside with a quantitative DNA marker.


Ordering information: Go to online ordering or download sample submission form

Indications for mutation analysis:

1. Testing of individuals with adenomatous polyps
2. Testing of first degree relatives of the affected individuals
3. Genetic counseling

Familial adenomatous polyposis (FAP) is a colon cancer predisposition syndrome characterized by the early onset of hundreds to thousands of adenomatous polyps throughout the colon. By age 35, 95% of individuals with FAP have polyps. If left untreated, patients with this syndrome develop colon cancer by age 35-40. APC-associated polyposis conditions are inherited in an autosomal dominant manner.

 

Asper Oncogenetics

Asper Oncogenetics

Pricing

Breast and Ovarian Cancer
Cancer Predisposition
Familial Adenomatous Polyposis
Fanconi Anemia
Lynch Syndrome/Hereditary Non-Polyposis Colon Cancer
Melanoma
Microsatellite instability
MUTYH-associated polyposis
Nijmegen Breakage Syndrome
Polyposis Syndromes
Thyroid Cancer
Whole Exome Sequencing

EMQN Certificate of Participation

Asper Oncogenetics is a set of genetic tests related to common and rare hereditary cancers, including colorectal cancer, breast and ovarian cancer, lung cancer, glioblastomas as well as cancer related syndromes.

We offer quick services for early diagnosis and estimation of disease risk. Early diagnosis of cancer is vital to improve the outcome of treatment and, therefore, prevent cancer related deaths.