GENORAMA^® GENOTYPING SOFTWARE^TM

Genorama^® Genotyping Software™ is designed for analysis of microarray-based resequencing or genotyping images. 

The software can handle images from any 4-color microarray imaging system (e.g.  Genorama^® QuattroImager™, PerkinElmer ScanArray) and enables a kilobase readout simultaneously from both DNA strands or analyses up to thousands of mutations (SNP markers) in a single window.

The images can be analyzed by sample (one set of four images corresponding to the sample) or by SNP-s / mutations (one particular position from each set of images through all the samples to be analyzed).

MAIN FEATURES

Different color scales (grayscale and a number of pseudocolor palettes)
Assisted grid setup, automatic alignment according to the signals on microarray images
Automatic spot identification, adaptive quantification and artifact filtering

FEATURES FOR ANALYSIS BY SINGLE SAMPLES

Signal intensities of four images are compared and automatically translated into the presence of a nucleotide(s) on the image and analyzed sample.

Automatic base calling
Histograms of relative signal intensities in different imaging channels
Comparisons with wild type or reference sample 
Highlighting dubious positions 
Different normalization methods of signal intensities between A, C, G and T channels 
Various formats for saving the results

FEATURES FOR ANALYSIS BY SNP-S / MUTATIONS

Real time comparison of all the array positions at all samples to be analyzed in visual as well as different quantitative formats.

Image database function and comparison of multiple images
Absolute and relative color scales of images, grayscale and pseudocolor visualization
Image filter 
Elimination of single bright pixels 
Genotyping by groups

For more information
Genorama^® Genotyping Software™ (pdf, 193 kb)

For ordering (incl. free demo CD) or inquiries, please contact Asper Biotech
info@asperbio.com