Traumatic brain injury complications – ApoE

The ApoE gene plays an important role in the maintenance, repair and growth of neurons. Patients with the ApoE4 genotype recover from brain injury much more slowly, have an increased danger of postoperative complications in cognitive functions, and also have a much worse general prognosis. The ApoE4 genotype is also associated with an elevated risk of late onset Alzheimer’s disease and coronary heart disease.

Asper Biotech has developed a genetic test for screening different ApoE genotypes (ApoE2, ApoE3, and ApoE4) by determining the two polymorphisms (rs7412 and rs429358) in the ApoE gene.

The test is recommended for brain injury patients and for people with Alzheimer disease as well as their relatives. Also, knowing the ApoE genotype can be important in studies of people with potential cardiovascular risk. Additionally, testing the ApoE genotype has prognostic value in the case of the athletes participating in high-risk sports in order to decrease potential damage factors.

The test is available with diagnostic package service (includes DNA extraction, genotyping, interpretation, hard copy of the results report).

 

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