Familial Adenomatous Polyposis – FAP
Familial Adenomatous Polyposis (FAP) is a colon cancer predisposition syndrome characterized by the early onset of hundreds to thousands of adenomatous polyps throughout the colon. By age 35, 95% of individuals with FAP have polyps. If left untreated, patients with this syndrome develop colon cancer by age 35-40. APC-associated polyposis conditions are inherited in an autosomal dominant manner.
The FAP test is a sequencing-based test to detect mutations in the adenomatous polyposis coli (APC) gene that is associated with FAP syndrome.
Molecular studies are recommended for planning an appropriate surveillance strategy and genetic counseling for the family. The test is available with diagnostic package service (includes DNA extraction, genotyping, interpretation, hard copy of the results report).
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